Contraindications
Individuals with known hypersensitivity to Paracetamol, Caffeine, or any other ingredients in this medicine.
Precautions for Use
Warnings
You should consult your doctor before using this medication if:
You have liver disease or are at risk, including alcohol-related liver conditions.
Although Paracetamol has no toxic effects when used at therapeutic doses under medical supervision, exceeding the recommended dosage can lead to liver damage. Simultaneous use of multiple products containing Paracetamol should be avoided to prevent overdose. Do not exceed the prescribed dosage.
Avoid consuming excessive amounts of caffeine (e.g., coffee, tea, or some canned beverages) while taking this product.
This medicine contains lactose. Patients with rare hereditary conditions such as galactose intolerance, lactase deficiency, or glucose-galactose malabsorption should not use this medication.
Use During Pregnancy and Breastfeeding
Pregnancy
The use of Paracetamol-Caffeine during pregnancy is not recommended due to the potential risk of weight gain and spontaneous miscarriage associated with caffeine consumption.
Breastfeeding
Caffeine present in breast milk may have a stimulating effect on breastfed infants.
Due to the caffeine content in this product, its use is not recommended during pregnancy or breastfeeding.
Effects on Driving and Machine Operation
This medication does not impair driving ability or machine operation.
Drug Interactions and Incompatibilities
Interactions with other medications and incompatibilities should be considered. Consult a doctor for detailed information.
Absorption Rate of Paracetamol
The absorption of Paracetamol may be increased by Metoclopramide or Domperidone, while it can be reduced by Cholestyramine. The anticoagulant effects of Warfarin and other Coumarins may be enhanced with prolonged and regular use of Paracetamol, increasing the risk of bleeding. However, occasional use generally does not have this effect.
Due to a lack of studies on incompatibilities, this medication should not be mixed with other medicines.
Side Effects
For Paracetamol
Uncommon (1/1000 < side effects < 1/100):
- Skin: Rash.
- Digestive system: Nausea, vomiting.
- Blood: Disorders in the blood production system (e.g., neutropenia, thrombocytopenia, anemia), leading to pallor or weakness.
- Kidneys: Nephritis or renal failure if used long-term.
Rare (side effects < 1/1000):
- Skin: Stevens-Johnson syndrome, toxic epidermal necrolysis, Lyell syndrome, generalized blistering rash.
- Other: Allergic reactions.
For Caffeine
- Nervous system: Nervousness, dizziness.
When recommended levels of Paracetamol-Caffeine are exceeded or consumed alongside dietary caffeine, it may increase caffeine-related side effects, such as insomnia, irritability, anxiety, headaches, digestive issues, and heart palpitations.
Management of Side Effects: Stop the medication and notify your doctor or pharmacist immediately in case of adverse reactions.
Dosage and Administration
- Adults and children aged 16 years and older: 2 tablets every 4 to 6 hours, up to 4 times per day. Do not exceed 8 tablets in 24 hours.
- Children aged 12 to 15 years: 1 tablet every 4 to 6 hours, up to 4 times per day. Do not exceed 4 tablets in 24 hours.
- Not recommended for children under 12 years old.
Note: Keep out of reach of children.
Read instructions carefully before use.
STORAGE:
In dry and cool place (under 30°C), protect from sunlight, transfer handle with care.
SHELF LIFE:
36 months since manufacture date.
A PRODUCT OF:
US MEDICOM COMPANY LIMITED
MANUFACTURED BY:
PHUONG DONG PHARMA CO., LTD
